Mad Doctor tells a story of a female surgeon who has lost her motivation to carry out surgery for patients. She decides to work in a small hospital in the countryside, running away from her dark past. There, she experiences all kinds of unbelievable incidents, from a patient crushed by a pig to one bitten by a penguin. Killer whales and crocodiles are also on the list. However, in this small hospital, where medical staffs are as helpless as those in the big urban hospitals, this female surgeon restores her passion for being a medical practitioner. Using her special skills and perseverance, she changes the medical conditions of the village, and regains the strength and passion she once had.